Docking-based virtual screening of potential human P2Y12 receptor antagonists
نویسندگان
چکیده
منابع مشابه
Docking-based virtual screening of potential human P2Y12 receptor antagonists.
Platelet plays essential roles in hemostasis and its dysregulation can lead to arterial thrombosis. P2Y12 is an important platelet membrane adenosine diphosphate receptor, and its antagonists have been widely developed as anti-coagulation agents. The current P2Y12 inhibitors available in clinical practice have not fully achieved satisfactory anti-thrombotic effects, leaving room for further imp...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2011
ISSN: 1672-9145,1745-7270
DOI: 10.1093/abbs/gmr023